The ideal treatment to address the challenges with numerous chronic disease would eliminate compliance issues, match the durability of chronic disease and be well tolerated by patients.

FGF21 is an ideal target to treat multiple chronic diseases. It has been shown to be well tolerated in large animal and human clinical trials. FGF21 also activates key pathways associated with numerous chronic diseases.

Utilization of liver tropic capsids encoding for secreted proteins minimize dose while delivering therapeutic protein to high percentage of target cells. Ensuring sustained, durable efficacy for patients.